Category archives: Technology

BOC Sciences: A Robust Isotope Labeling Service Vendor


New York, United States—May 10, 2022—BOC Sciences is a robust supplier of stable isotope-labeled compounds in the United States. While realizing isotopic labeling with different molecules could be tricky sometimes, the company provides professional stable isotope labeling services for worldwide partners to support them from preclinical to commercial stages.

 

Stable isotope labeling involves ...

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Innovative Impurity Isolation and Identification Techniques at BOC Sciences to Address Pharmaceutical Impurity Issues


New York, United States—June 30, 2022—BOC Sciences announced impurity isolation and identification services using traditional and innovative impurity techniques.

 

“We’re happy to have achieved consensus with global pharmaceuticals to deal with the NDMA risk and other impurity concerns. We will continue to provide full support taking advantage of our rich experience and ...

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BOC Sciences Demonstrates Comprehensive Strength with LYTAC Technology


New York, United States—June 29, 2022—BOC Sciences, a leading CRO in the pharmaceutical industry, demonstrates its comprehensive strength through innovative lysosome-targeting chimera (LYTAC) degradation technology solutions developed within the field of targeted protein degradation.

 

LYTAC is a new technology that can degrade extracellular proteins and membrane-related proteins through the endosomal/lysosomal pathway. The ...

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PROTAC-based Methods as Traditional PROTAC Protein Degradation Technology Alternatives


In recent years, the transition from inhibition of aberrant protein function to specific degradation of desired proteins with Proteolysis Targeting Chimeras (PROTACs) has resulted in remarkable progress and is currently affecting a paradigm shift in drug discovery and therapy development. PROTAC approach has allowed quick expansion of the “druggable proteome” beyond proteins that bear distinct ...

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Cell-Penetrating Peptides: Features, Mechanisms, Applications


Cell-penetrating peptides (CPPs) refer to water-soluble, partly hydrophobic, and/or polybasic short peptides that are fewer than 30 amino acids in size. Different types of CPPs like chimeric peptides and hydrophobic peptides have different lengths, charges, solubility, and hydrophobicity. At current, cell-penetrating peptides are often classified in line with their characteristics, including origin, conformation, and ...

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Four Well-Established Strategies Used in Hit Identification


The major preclinical phases of peptide drug discovery encompass initial target identification and validation, hit identification, high throughput screening, lead optimization, etc. Among them, hit identification is one of the most critical steps in identifying peptides that can interact with well-validated targets.

 

Hit identification (HI) follows the process of target validation, in which the compound ...

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Total Peptide Library: More Flexible and Productive


Peptides with low molecular weight have been known to be less allergenic and the diverse physiological roles of peptides make them suitable candidates for the development of therapeutic agents. Peptide drugs are widely used in the prevention, diagnosis, and treatment of diseases such as cancer, diabetes, and AIDS. However, the development of peptide drugs is ...

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Useful Approaches for Labeling Peptides with Fluorescent Dyes


Due to the high sensitivity, flexibility, selectivity, and environmental stability, fluorescent techniques are broadly applied in biological research. Peptides provide unique possibilities for the development of efficient and selective fluorescent sensors because of their modular nature, synthetic accessibility, and biomolecular recognition potential. Accordingly, labeling peptides with fluorescent dyes become a powerful tool for studying biologically ...

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A Low Temperature Vacuum Fryer


Fruits and vegetables vacuum frying machine

There has been a popular fruits and vegetables snacks vacuum fryer in the food process.

A vacuum fryer is a machine designed to fry vegetables, fruit, fish, and meat at low temperatures.

It has been found that vacuum frying lowers the release of carcinogens and promotes healthy and safe eating.

 

Guidelines for Retort Sterilizer Selection


food retort sterilizer

Heat sterilization is the unit operation in which foods are heated at a sufficiently high temperature and for a sufficiently long time to destroy microbial and enzyme activity.

General Guidelines for Retort Selection

In order to select a retort the follows should be considered:

• Shape and type packages, Metal cans, Glass jars or bottles, Flexible ...

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