Category archives: Science

BOC Sciences Highlighted Carbohydrates Harvest Admiring Fans at CPhI North America 2022


Global players in pharma supply chains witnessed the grand conclusion of the in-person meeting CPhI North America 2022 in May. BOC Sciences showed presence at booth 1319 and attracted many visitors who are influential researchers and industrial decision-makers.

 

CPhI North America holds the mission to facilitate the growth and evolution of ...

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BOC Sciences Is Fully Prepared for the BIO International Convention in June


As the BIO International Convention is about to open on June 13th, BOC Sciences is now ready for everything. It will showcase the newest breakthroughs in microbial fermentation technologies to global pharma leaders and peers, which can help them achieve scientific or business goals.

 

BOC Sciences has been longing for the opening of the BIO ...

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An Overview of Mainstream Carbohydrates in the Market


As one of the primary biomolecules in nature, carbohydrates are critical elements in nutrition provision, energy transportation, cell composition, etc. In view of their universality and essentiality in research, this article is an exploration of carbohydrates, especially those hot ones in the market.

 

Chemical Classifications of Carbohydrates

There are different ways to classify carbohydrates ...

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Peptides Labeling with Stable Isotope


Peptides are organic compounds formed by the dehydration of amino acids and intermediate products of protein hydrolysis. Peptides have strong biological activity, which can regulate the functional activities of cells in living organisms, and play a variety of roles in medicine, cosmetics, food, and other fields. With the more and more extensive and in-depth applications ...

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Antibody-drug Conjugates Manufacturing and Future Focus


Antibody-drug conjugates (ADCs) are formed by covalent biochemical conjugation of monoclonal antibodies (mAb) with payload drugs through small molecular linkers. They are regarded as an emerging class of drugs designed for high-specificity targeting and destruction of cancer cells, since the specificity of mAb to tumor cells allows small-molecule drugs to target tumor tissues, effectively reducing ...

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PROTAC-based Methods as Traditional PROTAC Protein Degradation Technology Alternatives


In recent years, the transition from inhibition of aberrant protein function to specific degradation of desired proteins with Proteolysis Targeting Chimeras (PROTACs) has resulted in remarkable progress and is currently affecting a paradigm shift in drug discovery and therapy development. PROTAC approach has allowed quick expansion of the “druggable proteome” beyond proteins that bear distinct ...

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Phòng khám Chiropractic ACC Quận 1 - TP.HCM


Tự hào là đơn vị tiên phong ứng dụng Trị liệu thần kinh cột sống, ACC đã điều trị thành công cho hàng ngàn bệnh nhân mắc bệnh cơ xương khớp, bệnh cột sống cấp và mãn tính mà không cần dùng thuốc hay ...

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Cell-Penetrating Peptides: Features, Mechanisms, Applications


Cell-penetrating peptides (CPPs) refer to water-soluble, partly hydrophobic, and/or polybasic short peptides that are fewer than 30 amino acids in size. Different types of CPPs like chimeric peptides and hydrophobic peptides have different lengths, charges, solubility, and hydrophobicity. At current, cell-penetrating peptides are often classified in line with their characteristics, including origin, conformation, and ...

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Four Well-Established Strategies Used in Hit Identification


The major preclinical phases of peptide drug discovery encompass initial target identification and validation, hit identification, high throughput screening, lead optimization, etc. Among them, hit identification is one of the most critical steps in identifying peptides that can interact with well-validated targets.

 

Hit identification (HI) follows the process of target validation, in which the compound ...

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Total Peptide Library: More Flexible and Productive


Peptides with low molecular weight have been known to be less allergenic and the diverse physiological roles of peptides make them suitable candidates for the development of therapeutic agents. Peptide drugs are widely used in the prevention, diagnosis, and treatment of diseases such as cancer, diabetes, and AIDS. However, the development of peptide drugs is ...

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